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HRT for 2 1/2 months, 2nd endo appointment later today, test results?

Started by Pipes, October 01, 2015, 02:27:06 PM

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Pipes

I am having trouble finding information online about where my levels 'should be' as I progress on HRT.

Basically, it would be nice to be able to go into my appointment with the knowledge of where I want my levels to be so I can advocate for myself with my endo who I have heard likes to play everything on the very conservative side when it comes to dosages etc.

I have been on Spiro (orally) 4x day (pills) & trans-dermal patches of Estradiol (changing 1x week).

My original Pre-HRT blood-work levels were as follows:

Test name                       Result    units      Ref.range
TESTOSTERONE, TOTAL       525     ng/dL      250 - 1100

Test name                Result    units
Estradiol                  20     pg/mL

Estradiol, Free          0.43     pg/mL

Test name                               Result    units      Ref.range
SEX HORMONE BINDING GLOBULIN   49      nmol/L     10 - 50
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KristinaM

I have no definitive information, but those numbers look pretty standard for a "male" body.  Bear in mind that blood hormone levels will fluctuate somewhat throughout the day though, so your T could be even a couple hundred points higher or lower if your blood were drawn at a different time of day.

But, every doctor is going to attempt to maintain levels within their own comfort zone.  Some will occasionally go outside that comfort zone (say, pushing E levels higher than "normal") in order to achieve feminization though.  Higher levels are not recommended though for health reasons, so the lowest dosage possible to attain adequate results is what they will shoot for, so numbers are almost irrelevant for feminization purposes, but should be monitored for health reasons.

With all that being said, I would say you're looking for Testosterone levels under 100 ng/dL, and Estradiol levels over 100 pg/mL, but those are just my gut-feelings.  I'm not familiar with Free Estradiol or SEX HORMONE BINDING GLOBULIN levels, and I'm barely familiar with the others.  :)

In the end, your doctor will monitor your levels and adjust your dosages accordingly to produce the best results.  You should trust them, not me.
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JennX

Google: Endocrine Society Transgender

1st link is their clinical guidelines for treatment. You may wish to print and share with your provider.

General Guidelines:

Serum Estrogen: 120-200 pg/ml
Total Testosterone: < 60 ng/dL


PS: They all play on the conservative side as they don't want to get sued. They don't want to loose their nice house, office, and job they worked many years to achieve. :)
"If you want the rainbow, you gotta put up with the rain."
-Dolly Parton
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