There are others who reported this...
it sounds like menopausal symptoms... either t high or e low...
one explanation might be oral/sublingual intake of estrogen only once or twice a day...
it might be possible to spread the daily dose in for example four smaller doses to avoid larger peaks and lows...
possibly same for the anti androgen...
like taking the daily spiro dose in for small parts instead of one big one...
spiro does not need to be taken sublingually
for more steady doses a part of it as patches or gel might be an option...
or weekly injections or implants....
as others have mentioned just talk it through with your doctor/endo...