I think the two main issues are the disparity between real-life and the internet, and passability. For the most part, people generally tolerate each other in civilized society. We know we're all just people getting by, and we usually leave each other alone save for isolated incidents. Everyone has their own opinions on everything and everyone but the reason our society is as functional as it is, is because we know being intolerant to everyone would be chaotic so we keep to ourselves (again save for isolated incidents). On the internet, we can let it out with a degree of detachment and anonymity. I don't think a lot of the disparaging remarks online against trans people should be taken too personally. It's entirely possible for someone to state a blanket opinion online and then be fine with an individual in person. The same goes for many other groups that are hated on.
Then there's the issue of passability. I hate to make it a thing, but people can be shallow on top of being judgmental. Having 'passing-privilege', I haven't had hardly any issues in transitioning. About 2-3% of men I've talked with online or in-person (out of a large pool of men) have had an issue with me being trans. However, this is usually after they find out that I'm not cis. And even then, I'd say half of that 2-3% end up being curious and at least try to be respectful as they ask questions and try to educate themselves. So I've experienced a lot of tolerance and admiration. Far more than I expected when I started out. But again I believe this is because I pass and am attractive.
That's my perspective anyway. I'm sure others will feel differently.
Mod Edit singling out groups removed