I had a twice-a-week patch for a while, made by Sandoz. For about a month and a half, I alternated sides on my butt. The patch material is plastic which doesn't stretch or breathe, and over the course of 3-4 days, the skin underneath was red, itchy, irritated and one time, a pimple developed under the patch and turned into a huge abscess. I placed the last patch I used on the side of my torso. A full month later, I still had hives where that patch had been. The skin on my butt is nearly healed, and the hives on my side have finally diminished. Never again!