Hi,
It really depends and everyone is different. I have been on HRT for close to 3 years at a transitioning dose. My T was at 20 to 36 ng/dl for a year and below 3 for about 2 years. My sex drive is very low and orgasm is getting to the point of needing a lot of stimulation. My gonads have reduced in size greatly as well as my scrotum. My penis has lost about half in length and girth.