Well, dysphoria, or feeling very anxious is the psychological effect of our condition which is biological. In that sense, our dysphoria causes metal problems, an illness. Similarly, when I experience bereavement I might get mental problems. Not insanity, but problems in functioning normally which we can classify as being ill, not feeling well. Our remedy is not taking medicines to modulate our brain, but seeking therapy and surgeries where applicable. Few people are truly mentally ill in the sense of being completely out of touch with reality, and if they are, then this has a biological cause and a chemical origin.
We're still stuck with this conundrum of semantics, logical fallacies, miscellaneous buzzwords, gender politics and stigmas, which makes it difficult to get a logical picture of the issues we're trying to explain and convey.