Hello everyone,

hope some people here can help me to get more details and ideas.

I have 3 main problems/questions:

Adrenal overdrive:
Its a known fact that your adrenal glands temporarly goes into overdrive after SRS. Mostly this goes down after a few month. I'm 10 month postOP and my adrenal is still producing too much adrogenes and i dont belief it will go down at anytime. Is it a trauma in some sections? DHEAS for example is higher than shortly after SRS - no signs of decreasing. The problem of this desease is that too much androgenes causes more bodyhair, hairloss, a more masculin face ... you all know it. Actually I'm taking dutasteride dialy to reduce the effects. Dont know if it works ...

Thyroid:
After having another research i was found this topic here:
https://www.susans.org/forums/index.php/topic,137577.msg1662608.html#msg1662608
"EVERYONE TRANSITIONING needs to be aware of our risk for THYROID DISEASE!!!"

I'm not sure. I also have a light thyroid underfunction but i would'nt see the reason here for my massive andrenal overdrive. All in all this is mysterious. My andrenal glands get no order to produce more androgenes - ACTH is very low. On the other hand I cant belief that i should have an cancer. WHAT gives the production order?

Prolactin:
The next mysterious thing is my prolactin level and its trigger-sensity is very high (levels still around 150ng/ml,  I have no prolactinoma, stopped CPA a few weeks ago). Does anyone no if prolactin triggers the andrenal androgene production? Could this be a missing link?

Taking CPA will rise my levels up to 200 ng/ml. How could it be? This is a big problem in the treatment of hyperandrogenism caused by the andrenal glands why i have to take another antiandrogene or something like dutasterid. As you can see - its a cycle. The treatment of one problem will cause another one.

I'm very sad about this development after SRS ... 

Mod edit: No dosages as per Terms of Service #8

I am always wary of one size fits all solutions to problems and I am not medically trained, but has your doctor considered a pituitary tumor. The Pituitary gland controls a major portion of the things that go on in the body and a problem there could explain the weird mix of symptoms that you are having.

No, ive no prolactinoma (see above). The high prolactin was caused by Androcur, serum levels decrease at the moment. The problem isnt the high prolacin but the adrenal overdrive.

Consult your doc and get some imaging studies done to rule out tumors of the pituitary gland and adrenals.

I dont think its a cancer. My doc still doesnt know what's up there. Thats why iam asking here.

Not all the growths in the body are cancer. In addition, it could be a malfunctioning Pituitary gland that is throwing the balance of your body out. Hormones are not always controlled by the gland that produces them. Often the Pituitary gland sends out a control hormone that regulates the gland that produces the hormone. When you have more than one level that's incorrect, you want to look for a common cause and the Pituitary gland is a good place to start.

Quote from: Dena on June 26, 2016, 05:24:29 PM
Not all the growths in the body are cancer. In addition, it could be a malfunctioning Pituitary gland that is throwing the balance of your body out. Hormones are not always controlled by the gland that produces them. Often the Pituitary gland sends out a control hormone that regulates the gland that produces the hormone. When you have more than one level that's incorrect, you want to look for a common cause and the Pituitary gland is a good place to start.

Like I said:

QuoteMy andrenal glands get no order to produce more androgenes - ACTH is very low.

I had an MRT 1 week ago - theres nothing in my head.

Why should any unnormal growth (f.e. hyperplasmia) exactly started with SRS? I'm convinced that its has to do with SRS. As far as i know prolactin increases production of andrenal androgenes - so it could be another reason. But why my prolactin is so high? Ive no prolactinoma, no CPA ...? Only estrogen and progesterone. 

Androgenes destroy my body and nobody can help. I mean everybody asks why i want to commit suicide -> that is the reason. Cause nobody can help me - no doctor, no specialist, no facebook group, no german board, no english board. Nobody from 7 billion people is able to help me. Thats why i dont want to live anymore. Its that simple. 

Perhaps KayXo would have some thoughts on the subject. You may want to PM her.

Do you really think a PM will change anything? SRS destroyed my life. In every case.

KayXo is very knowledgeable. Yes, I do think it will make a difference.

I was thinking about this problem. I am not a doctor so this is just my thoughts. Perhaps Spironolactone would make your brain think you no longer need higher levels of T and reset your adrenals to normal.

Anyhow, the real solution is to see other endo's till you find one that can help you.