the people I grew up with know that I've drastically  changed , but I haven't talked to them in a very long time and had stopped communicating do to just moving on and not related to transition.

The only person I lost so far is my wife. Everyone else is supportive and some of this friendships grew stronger in the past couple of months. I'm eager to see what the future brings.

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True friends will always support you

Alice x

Losing friends: No
Family: Yes

A few people who were only acquaintances, but no actual losses of note. If someone cares that much about my gender then they aren't worth keeping anyway.

The people I care about know. Others, If they can't accept it they were not good friends to begin with.. Actually now that my introvert personality  on the wane I fully expect to gain more.

As far as I know I've lost no one and gained many. Female me is much more outgoing than pseudo-male me was and I've made many new friends. One even told me on Friday that she considers me a best friend. True, my marriage has failed, but my ex-wife-to-be is still my very best friend and roommate. The only thing that has really changed is separate bank accounts and lack of sex. With her medical problems and the way my testosterone was dropping PRIOR to HRT that was a sometimes thing anyway.

I have gained so much. Relationships have been strengthened. As far as I know, I have lost no one. Correction, I did lose one lost sole who used to sleep in my bed, drive my car, eat the same foods I do, but I don't miss him a bit.
Monica

By the time I started blossoming into who I am, I lost all contact with everybody I had previously known. Since then, I found my biological family and new friends, so all is good.

When I switched to a new Facebook account under my new name, I did take the opportunity to drop a couple people who'd annoyed me for years, but I don't think that counts. Otherwise, no; if anyone had a problem with me, they were polite enough to keep it to themselves, and I really don't think anyone did.

I haven't encountered past friends as of yet even though I know they know , so I have no idea of how they feel. My new friends all accept me as do most anyone I deal with on a day to day bases.

No real loss. Perhaps a couple relationships are more distant, but i had only one instances of anyone being semi non-accepting and he later apologized and said it was because he felt weird being attracted to me. Appreciated the honesty and we remain friends.

I lost a couple (literally, a married couple), though they would deny that it had anything to do with me being trans. All I know is there was no trouble *before* I came out to them, and a whole bunch after. My ex-girlfriend stopped talking to me, too. Other than that, nobody... and in fact, most of my family has been more supportive than I expected them to be. So all in all, I think things turned out pretty well.

3 people specifically.
A friend from high school, who deleted me shortly after I started transitioning. Funny, because most of the Punks I know tend to be supportive or open minded. We weren't close though so it didn't hurt.

A girl from the local club scene, also not a problem because people don't really like her as she tends to hyper aggressive and overly dramatic.

The last one was a bit more painful, as it was a closer friend that I'd actually visited and hung out with. He had gone to shows that me and my friend played with us, met up at movies, I'd gone out to dinner with him (as a group, not a date), literally someone from an inner circle of friends that I hung with who just deleted me out of the blue after I started transitioning. 

Now. On the other hand there are people I personally chose to disconnect with.
As a woman I feel weird hanging with some of my old guy friends. They know I'm interested in men, I don't want to send them the impression that I'm interested in that way with them, others I already had problems with due to the occasional bit of misogynistic vomit that seems to roll out of them and I decided to just cut ties to make things easier on myself. It's hard to be around someone who constantly bags on your values, or doesn't have enough respect for women. Can't say that I miss them but there is a weird space were sometimes I feel guilty for never seeing them. There were times when we had fun together, but most of the time it was toxic and hard to be around.

That's how I feel about it as far as past friends I grew up with. I'm sure they wouldn't say anything , but I sure would feel awkward.

I answered "more than expected". It's not that the number is large, rather the people who turned sour came as surprises - albeit expected surprises, I'd understood that coming out experience is quite varied.

The main and seemingly irreversible split was with my sister, who didn't approve of my coming out as bisexual and involved in bdsm/leather. What shocked me was she really blew her cork over my consideration of GCS. We've not spoken since - 17 years.

The discussion at work was uneventful aside from a guy who expressed he didn't think this happens so late in life -- I don't much expect people to be clueful.

When it came to casting a wider net I decided to announce the decision to start transition in a group chat including the 50 or so closest friends who didn't already know or are too far away to see face-face and the responses were all welcoming and supportive. I was a bit surprised at the people who simply left the conversation without acknowledging, none of whom are all that close but some of whom I'd have expected to be outgoing. None of these has been in contact since and I don't know whether they're people who considered it a TMI or simply didn't want the interruption or whatever.

And then there are the people who are close and I talked to in person and acquaintances who commented on seeing the changes in my appearance (the latter were all surprised and also fine about it).

The only problem was with a close friend who runs a facility I work in often and there were some standing problems there. One day there was a particularly difficult discussion and I was quite emotional - hardly unusual for me even before starting estrogen.

He asked me if I was "so emotional because of the medication I'm on?" since I'd told him I was transitioning a month before, he knows about estrogen but I was in no way prepared to hear the equivalent of "are you having your period?". I could only interpret this as a cis-sexist assumption that as he interpreted me as male it would be ok to say something that he wouldn't ever have said to a cis female.

I was so shocked that I didn't address it then and did later so I could take it up with him without other issues being part of the conversation. Unfortunately he doubled down and claimed both that it wasn't an intrusive question and that he had the right to ask it anyway.

So friendship there is on hold at best.

I didn't lose very many friends in a bitter, nasty way. It was more due to a natural and somewhat gradual change in interests and lifestyle. I wanted to develop my friendships with my women friends and that meant spending more time with interests that I did with my women friends.

I didn't set out to lose friends from my previous life, but it did happen.

I can say technically lost none, but I voted other.. let me explain.

I only really had one friend when I started before HRT and she supported me 100%, she actually encouraged me to explore my gender..