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Is it possible to become immune to estradiol and spirinolactone?

Started by Angélique LaCava, November 29, 2016, 11:31:46 AM

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Angélique LaCava

Can't remember if I asked before, but it's something I wonder and worry about.
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Jean24

I had asked a similar question before because I was getting so little out of HRT - and testosterone before it. I have kinda wide hips, and I was always very thin before starting HRT at 27. Since not much had changed, I was starting to really wonder.
Trying to take it one day at a time :)
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Angélique LaCava

A few years ago there was a girl on the forums that I'm not sure is still on who said something about her hormones not working anymore. I think her name was Rowan.
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Jean24

Quote from: Angélique LaCava on November 29, 2016, 03:21:56 PM
There was a girl on the forums that I'm not sure if is still on who said something about her hormones not working anymore. I think her name was roe.

It is possible. Some people are insensitive to estrogen but it's really rare and she probably would have never had any effects from HRT rather than her having some effects, then having no effects.
Trying to take it one day at a time :)
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KayXo

If levels are too steady, tissues may become desensitized, it seems.
I am not a medical doctor, nor a scientist - opinions expressed by me on the subject of HRT are merely based on my own review of some of the scientific literature over the last decade or so, on anecdotal evidence from women in various discussion forums that I have come across, and my personal experience

On HRT since early 2004
Post-op since late 2005
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LiliFee

Perhaps this is one of those typical questions that shouldn't be asked to us lay-people, but to a proper endocrinologist ;)

Having said that, there is anecdotal evidence of desensitization. These are people like us though, who, for better or for worse, have seen their breast growth stalling before the desired result. Whatever. People are inclined to see dragons and monsters where simple solutions exist.

Go and ask your doc, I'm sure there are answers out there. What I do know, is that the human body is a very, VERY complex system and it works differently for each and everyone for us.
–  γνῶθι σεαυτόν  –

"Know then thyself, presume not God to scan, The proper study of mankind is Man"
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