Quote from: Dena on March 01, 2017, 03:30:28 PMI am dealing with a person who wants to dose me low because of DVT risks of which I am very unlikely to develop because of my health and history.
It's unfortunate if a higher dose proved more effective but based on your feedback, it would seem you are doing well on your current dose.
Have you showed the studies which show that, even in men of an advanced aged treated for prostate cancer, a high dose of estradiol patches with levels between 300-600 pg/ml did not result in thromboembolic complications and that researchers even concluded that this treatment may even be protective? What about the study where transsexual women of whom 13 out of 162 had a predisposition to DVT (activated protein C resistance or protein C deficiency) did not develop any complications despite being on a dose of transdermal estradiol higher than what is typically prescribed to post-menopausal women? Is your doctor aware of the very low incidence of DVT during pregnancy despite the very high levels of estradiol or during oral administration of bio-identical E2 in transsexual and ciswomen despite higher than typical doses for post-menopausal, sometimes MUCH HIGHER?
I believe it is important (and I know I'm repeating myself) to educate our doctors in the interest of our population and the generations to come.
Quotewith your levels, we should be able to determine if you are on track or not.
We have no way of knowing what levels are optimal for a given person as everyone is different and their sensitivities vary. Levels also fluctuate in time so tests are not necessarily accurate. Only the individual and their doctor can determine if they are on track or not by gauging how the body is responding (breast growth, hair patterns, fat distribution, testicle size, body odor, skin texture, etc).