Has anyone expiriance with Topiramate and hrt?
My Gp gave it to me for very awful migraines but im not sure how it goes along with hrt, he said its ok, but i rather hear it from some who also took the combo and it was fine

I get migraines frequently & have headaches every day (generally minor & tolerable) and my doc put me on that too.. For ME it caused severe memory loss & I felt like I had early alzheimers.. it was horrendous and only got worse the longer I was on it.   It didn't help the headaches one bit.  Ironically getting my hormone levels higher helped reduce my headaches far more than migraine medicine did. 

Thank you for reply, have you took it along with hrt or pre hrt? And when you wean off was it hard?

I just cut off meds cold turkey like you should never do lol.  Even HRT when I went off it (several times over the decades).  I didn't suffer any ill effects, but I did notice an almost immediate improvement in my memory retention.. which left me VERY grateful that it didn't have any lasting ill effects.

SO far the only med that seems to scratch the headaches was Depakote... a med generally given for bipolar.  And of course being on HRT greatly diminishes them.  My body is odd though, in that I took a 'baseline' after beeing off hrt 3 months for FFS... and I do produce at least enough estrogen to be considered generally above post-menopausal women.  (50 ng/dl or w/e the measured units were).  I still don't have enough though to stave off bone loss, so I take it.  My head definitely agrees with me taking it, that being said. 

I highly doubt it is psycho-somatic either, there is a definite improvement of symptoms (though I still get bad days) back on HRT.  I don't think it has anything to do with any other potential health issues or mental issues at this time.

I've been post op GCS since 2001, and that was around when I was 27 years old.  I'm 43 now. If that helps any.