I have never noticed this before I started binding, but my chest is compleeeetely uneven, my right is bigger than my right.  Putting it in a binder is really awkward, and I can't figure out how to situate them in the binder.  It looks rather awkward though, like it will either stick out further, or hang down lower depending on the position I place them...

Anyone else have/had this problem and have good tips?  Or should I deal?

Boobs from what I understand are never exactly the same size. Mine were different sizes and I just dealt with it and got surgery.

Yeah my chest is uneven too, it's very common. I think when wearing a binder readjusting a bit it's just one of these things you have to do. I wear a GC2B binder which binds a lot better than an Underworks and so I find I don't have to readjust nearly as much.

I think everyone's are to some extent but for most the difference is not very noticeable .  There are a few where the difference is a 2-3 cups sizes and is a problem for them.