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Low dose HRT a myth?

Started by Elli.P, May 15, 2017, 08:50:55 PM

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Elli.P

Went to first endo appointment last week. Asked to be put on low dose. She said there's no such thing, you either take a transition dose or you don't. You are either ready to transition or you're not. She said no estrogen because YMMV with every person and even the lowest of dose could be enough to transition.

So, is low dose real or is it something made up by the people that self medicate?

Does anyone have a website I can give the doctor for in site into what it is?

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Started Laser hair removal: 15 Nov 2014
Came out to Wife: 30 June 2015
Joined Susan's Place: July 18, 2015
Started growing out hair: 5 Jan 2016
Started HRT: 8 July 2017
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Pisces228

I don't think it's a myth.  As long as your testosterone is in the female range and your estradiol is over the normal male range I would think you'd see some results.   My testosterone hasn't dropped super low yet and my estradiol hasn't been super high, but they are both smack dab in the middle of the female range and I have had lovely results.  I am on a moderate dose of E.
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Dena

Your doctor is correct in saying any dose can bring changes however the rate of change will vary depending on the dosage. I have spend a fair amount of time on quarter dosage because of treatment standards and I continued to develop. I am now at half dosage and seeing additional development that didn't take place at the previous dosage.

You should discuss when you want to go public and that may give your doctors a better estimate on the rate of development you desire.
Rebirth Date 1982 - PMs are welcome - Use [email]dena@susans.org[/email] or Discord if your unable to PM - Skype is available - My Transition
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jentay1367

If you have youth on your side and a highamount of HGH you can get some stuning results on a low dosage of E and AA. On the other hand, if you're older, I think a low dosage is completely plausible. A small amount to ease the dysphoria could be used and no one would probably be the wiser for some time, if not in perpetuity.  It's true that YMMV, but it's a little easier to predict outcomes with HRT one you're of a certain age.
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AnonyMs

Its not a myth.

https://www.susans.org/forums/index.php?topic=130268.0

My endo does it, and he has literally 3500 trans patients. I'm pretty sure he knows what he's doing.

Saying you're either ready or not is also gatekeeping. I've been on HRT 8 years, and not transitioned. If a doctor said I'm not ready I'd just fire him and get another one.
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Johanna M

I have been on low dose spiro for the last half year or so and on a really low dose of E for three months.
Didn't think there would be much of a change but there has been. Quite a lot actually so that my plan to be in male mode at work for the next year is going to be difficult. So i guess that your endo could have a point in her saying that a small dose of E would be enough for (slow) transition.
One unexpected reaction after starting E  has been that i want to speed transition up.

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Megan.

This is purely my observation from others that have posted here,  but low dose does seem more like a stop-gap thing. It can buy you months or even years,  but does not appear to be an option 'forever'. I used it myself as a diagnostic tool,  but only to help validate that a full transition was something I needed to try.

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KayXo

Quote from: jentay1367 on May 16, 2017, 01:42:01 AM
If you have youth on your side and a highamount of HGH you can get some stuning results on a low dosage of E and AA

I recently came across one such study where young transgirls were put on a low dose of E and a potent AA with disappointing results in terms of breast growth. In author's words "with objectively small and subjectively unsatisfactory breast volume in most cases." And later they state "it has been hypothesized that breast growth might be more pronounced when CSH treatment is started earlier.24,27 This could not be confirmed in our study, because the obtained breast volume was limited in many trans-girls, or at best moderate in some, and most trans-girls expressed a desire for later breast augmentation surgery. This is similar to results in adult transwomen.24"

Time and time again, I've seen much older gals having much better results compared to younger ones.
I am not a medical doctor, nor a scientist - opinions expressed by me on the subject of HRT are merely based on my own review of some of the scientific literature over the last decade or so, on anecdotal evidence from women in various discussion forums that I have come across, and my personal experience

On HRT since early 2004
Post-op since late 2005
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jentay1367

Quote from: KayXo on May 16, 2017, 09:55:10 AM
I recently came across one such study where young transgirls were put on a low dose of E and a potent AA with disappointing results in terms of breast growth. In author's words "with objectively small and subjectively unsatisfactory breast volume in most cases." And later they state "it has been hypothesized that breast growth might be more pronounced when CSH treatment is started earlier.24,27 This could not be confirmed in our study, because the obtained breast volume was limited in many trans-girls, or at best moderate in some, and most trans-girls expressed a desire for later breast augmentation surgery. This is similar to results in adult transwomen.24"

Time and time again, I've seen much older gals having much better results compared to younger ones.

Frankly, I don't measure femininity by a big rack. YMMV.
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staciM

#9
All this talk of "quarter dose", "half dose", "low dose", "full dose" etc <seems silly>.   One Dr's low dose may be another Dr's standard or vice versa.  It's impossible to compare experiences<mod edit>.


Moderator Edit: This post has been edited.
- Staci -
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AshleyP

#10
Quote from: staciM on May 16, 2017, 11:29:31 AM
All this talk of "quarter dose", "half dose", "low dose", "full dose" etc <seems silly>.   One Dr's low dose may be another Dr's standard or vice versa.  It's impossible to compare experiences<mod edit>.


Moderator Edit: This post has been edited.

I think a "low" dose is the same as an eighth dose, but I'm not sure. :)

All the best,
--AshleyP
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Laurie


Hi folks,
  I thought I would put in my two cents on the dosage subject. There are charts available on the internet that show the generally accepted normal dosage range. As Staci said this is not necessarily what any particular doctor mar consider a "normal" range. Until there is a widely accepted standard you will need to ask your doctor what their definition of it is. I myself have not asked my doctor what he uses for his scale. He has used the term "Full" dose and I do not know what that is. This will change at my next check up on Monday.
  That being said I am taking the lowest dose on the "normal dosage" scale I have seen online. I would think a "low dose" would be a fraction of that.

  Hugs,
    Laurie
April 13, 2019 switched to estradiol valerate
December 20, 2018    Referral sent to OHSU Dr Dugi  for vaginoplasty consult
December 10, 2018    Second Letter VA Psychiatric Practical nurse
November 15, 2018    First letter from VA therapist
May 11, 2018 I am Laurie Jeanette Wickwire
May   3, 2018 Submitted name change forms
Aug 26, 2017 another increase in estradiol
Jun  26, 2017 Last day in male attire That's full time I guess
May 20, 2017 doubled estradiol
May 18, 2017 started electrolysis
Dec   4, 2016 Started estradiol and spironolactone



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AnonyMs

I regard low dose as a dose that is less than what you'd take if you were planning on physically transitioning and is less than is fully effective for that purpose.

Typically its just enough to get the mental effects, but no more, to minimize the physical effects.
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Elli.P

Thanks everyone for replying and thanks for not listing dosage. I had read about low dose HRT on this forum and other websites but had not really found any medical articles (go figure medical for trans sucks).

I don't know what the deal was with this Doctor. She mentioned "there are legal matters to consider" several times and kept looking at me weird (she has other trans patients and she is LGBT herself). Almost like she thought it was a sting operation or something. Lol, maybe I look like a cop with my long hair, plucked eyebrows and ear rings. I am in Texas so maybe she was worried I was an undercover reporter or something.

IDK, it was my first appointment. She ordered blood work to see where I'm at hormone wise and she said she would call with the results. Maybe the second appointment will go better.

Normally with people like that l kill them with kindness. But, I was nervous. Otherwise, I would have asked her if she was having a bad day and offered support. Or cracked a joke to lighten the tension.

We will see, I guess!

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Started Laser hair removal: 15 Nov 2014
Came out to Wife: 30 June 2015
Joined Susan's Place: July 18, 2015
Started growing out hair: 5 Jan 2016
Started HRT: 8 July 2017
  •  

Janes Groove

Quote from: AnonyMs on May 16, 2017, 01:03:46 PM
Typically its just enough to get the mental effects, but no more, to minimize the physical effects.

If this is true then how can one be sure it's not just a "placebo effect?"

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AnonyMs

Quote from: Jane Emily on May 16, 2017, 02:03:17 PM
If this is true then how can one be sure it's not just a "placebo effect?"

Does it matter?
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Devlyn

Definitely not something made up by people who self medicate.

Hugs, Devlyn
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AnonyMs

Yeah, definitly not made up. There's no doubting when you try it, and even less if you try stopping.
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KayXo

Quote from: jentay1367 on May 16, 2017, 11:24:34 AM
Frankly, I don't measure femininity by a big rack. YMMV.

In this study, not even a decent size was achieved. Feminization includes breast growth but other factors, as well, yes but since you mentioned HGH (human growth hormone) and followed it with stunning results, I thought you were referring specifically to breast growth.

Quote from: rachel.i. on May 16, 2017, 01:08:58 PMhad not really found any medical articles (go figure medical for trans sucks).

In journals, there are at least 100 articles/studies on transsexual hormone therapy, if not, much more. You just have to search on google scholar or pubmed and you will find, if you have the time. Recommended doses are mentioned there or doses used for that particular study and they may vary from one study to another, sometimes quite strikingly.

I am not a medical doctor, nor a scientist - opinions expressed by me on the subject of HRT are merely based on my own review of some of the scientific literature over the last decade or so, on anecdotal evidence from women in various discussion forums that I have come across, and my personal experience

On HRT since early 2004
Post-op since late 2005
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Melanie CT

Quote from: rachel.i. on May 16, 2017, 01:08:58 PM
Thanks everyone for replying and thanks for not listing dosage. I had read about low dose HRT on this forum and other websites but had not really found any medical articles (go figure medical for trans sucks).

I don't know what the deal was with this Doctor. She mentioned "there are legal matters to consider" several times and kept looking at me weird (she has other trans patients and she is LGBT herself). Almost like she thought it was a sting operation or something. Lol, maybe I look like a cop with my long hair, plucked eyebrows and ear rings. I am in Texas so maybe she was worried I was an undercover reporter or something.

IDK, it was my first appointment. She ordered blood work to see where I'm at hormone wise and she said she would call with the results. Maybe the second appointment will go better.

Normally with people like that l kill them with kindness. But, I was nervous. Otherwise, I would have asked her if she was having a bad day and offered support. Or cracked a joke to lighten the tension.

We will see, I guess!

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I was started on a low dose and it was increased a little so maybe I'm on a medium dose.


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