Quote from: Marcus O on December 18, 2017, 10:46:55 AMhe told me that he couldn't do estrogen if I had high blood pressure.
As long as bio-identical estrogen is prescribed, the scientific literature seems to indicate it's actually beneficial. Perhaps, you can share the following with them or go see another doctor who may be more familiar and up-to-date with ERT.
Menopause. 1998 Summer;5(2):79-85."The administration of (...) sublingual estradiol to 24 postmenopausal women (aged 48-58 years) was followed 60 min post-dose by a surge in mean estradiol serum levels (1759 +/- 704 pg/ml)."
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At rest a slight drop in systolic and diastolic blood pressure was measured after estrogen ingestion: 132 +/- 24 mm Hg versus 127 +/- 21 mm Hg, p < 0.05; 83 +/- 11 mm Hg versus 78 +/- 10 mm Hg, p < 0.02. There were no changes in resting heart rate, double product, or vascular resistance. The left heart cavities became smaller: the left atrium diameter decreased from 33.7 +/- 4 mm to 32.3 +/- 4 mm, p < 0.01; the end-systolic diameter decreased from 24.9 +/- 3 mm to 23.6 +/- 4 mm, p < 0.01; the end-diastolic diameter decreased from 44.5 +/- 4 mm to 42.7 +/- 4 mm, p < 0.01. The peak aortic blood flow velocity fell from 120 +/- 19 cm/s to 116 +/- 22 cm/s (p < 0.05), and the flow velocity integral fell from 26.3 +/- 4 cm to 24.9 +/- 5 cm (p < 0.01); the cardiac output underwent a small change, with borderline significance: 7 +/- 2 L/min versus 6.7 +/- 2 L/min, p = 0.06. Only minor changes in the hemodynamic and echocardiographic parameters were recorded after estrogen for both isometric and dynamic exercises. Analyses were also made for two subgroups: 13 normotensive women were compared with 11 hypertensive women. The post-estrogen decreases in resting blood pressure and in peak blood velocity were observed only in the hypertensive subjects, whereas the changes in heart dimensions and in flow velocity integral were the same in both subgroups."
Ann Clin Res. 1983;15 Suppl 38:1-121."Blood pressure, central hemodynamics and peripheral blood flow were measured at rest in 20 normotensive and 20 hypertensive postmenopausal women during cyclic placebo/estradiol-17 beta treatment."
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Estradiol-17 beta substitution decreased the systolic and diastolic blood pressure in normotensive, hypertensive and borderline hypertensive postmenopausal women."
Horm Mol Biol Clin Investig. 2014 May;18(2):89-103."The cardiovascular protection observed in females has been attributed to the beneficial effects of estrogen on endothelial function."
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estrogen alone or combined with progesterone has been associated with decreased blood pressure"
"Estrogens physiologically stimulate the release of endothelium-derived vasodilator factors and inhibit the renin-angiotensin system."
Climacteric. 2013 Apr;16(2):265-73."Estradiol decreased systolic blood pressure, plasma aldosterone levels, and the expression of renal sodium transporters."
Obstet Gynecol. 2015 Mar;125(3):605-10."In transgender women, estrogen therapy, with or without antiandrogen therapy, was associated with lower BP."
"Both systolic and diastolic median blood pressures in this group dropped significantly from baseline to 6 months (130.5 mmHg (IQR 11.5) to 120.5 mmHg (IQR 15.5) p=.006; 78 mmHg (IQR 21) to 67 mmHg (IQR 12), p=.001 respectively)."
The anti-androgen prescribed was spironolactone and this usually reduces blood pressure.
Maturitas. 1979 Jun;1(4):287-94."Haemodynamic changes during a 3-wk treatment with oestradiol valerianate (...) were studied in 12 postmenopausal women by isotope 113Inm radiocardiography. Systolic blood pressure measured in the supine position decreased during oestradiol treatment by 3% (P less than 0.05) and the diastolic blood pressure decreased by 4% (P less than 0.01)."
Circulation. 1987 Oct;76(4):753-8."We conclude that both oral and percutaneous treatment with estradiol may provide protection against the age-related increase in diastolic blood pressure observed in early postmenopausal women."
Quotethey only took my blood pressure once on one day and have made a judgement
Blood pressure can fluctuate a lot and increase due to stress, being in the doctor's office. My doctor took my blood pressure 2-3 times, standing up, sitting down, etc...and admits that only taking once may not be reliable. The ideal conditions, in the opinion of my doctor are that one should take it when relaxed, at home.