Gene behind female-to-male transsexuality identified
Thaindian News
July 30th, 2008 - 1:08 pm ICT by ANI

The variant was discovered by a team led by Clemens Tempfer, after they examined samples from 49 female-to-male (FtM) and 102 male-to-female (MtF) transsexuals, as well as 1669 non-transsexual controls.

The variant was found to be more common in men than women. However, it doesnt seem to be implicated in male-to-female transsexuality (MtF) as the proportion of MtF transsexuals with it was similar to that in non-transsexual men.

So there is this gene that is found in men more then women.  MTFs have it at about the same rate as men.  FTMs have it more frequently than women.  The gene effects concentration of sex hormones in tissue.

This is not the end all/be all though. The sample size of transsexuals was too small to be overly representative. Others will have to try and replicate the findings as well. While this may eventually point to a reasonable biological factor, it will be some time before things are confirmed enough to be treated as a truth.