Pretty much, they lost my respect in 2000 when the president at the time claimed to be one thing and then showed himself to be something totally different. Then we had John Ashcroft, the Patriot act, Guantanamo bay cuba, secret searches, secret courts, Secret prisons, Arresting Americans in America and denying them their constitutional access to the courts, lies to go into Iraq, Torture, Secret rendition, Outing a CIA agent, All the corruption, Katrina, Warrantless spying on Americans, Abu Ghraib, Haditha, Iran, tax cuts for the wealthy, the supreme court, I could keep going.
As things stand now my vote will be for anything but Republicans. Now that might change if a republican worthy of my vote runs but I seriously doubt that happens with the religious fundies in charge of their party.