The city of Gainesville, where UF is located, tends to vote very liberal.
Alachua County, where G'ville is located, in the rural areas trends more conservative. McCain probably lost 55-45 in the rural areas but Obama won something like 85-15 in the G'ville city limits.
Given Obamas GOTV and voter reg. efforts this will be a matter of convincing college students to go back to the polls.
Good news is UF has a very active and influential GLBT Student Union. I seem to remember that the Sororitys had a close relationship with the GLBT. Quick math is something close to 5,000 votes right there.
Also a good portion of the Professors and Admin types at UF live within the city limits.
The wild card in this type of election is actually the Afric. Amer. vote. Though they voted 98-2 for Obama, they trended to vote for gay marriage bans at rates close to 70%.
In Florida the gay marriage ban might not have reached 60% without a large black turnout.