I have one son... if you can consider infertility treatments "the old fashion way" (it was through intercourse, not IVF). Given the choice to have transitioned earlier in life, I still wouldnt trade him for that option. Course, being divorced, I could have done without meeting his mother...

Although I am 45 (I consider that young), I am comfortable at this point with the idea that transitioning will end any possibility of raising biological kids. But I wouldnt rule out adopting or raising step children with a partner to share my life with.