I have been following this game for a little while now, and it's nearing the open beta phase so I'm getting excited enough to want to talk about it!

It's set 30 years after Star Trek Nemesis, and the two factions are Federation and Klingon which are apparently at war in this setting. Half the gameplay is flying your ship around space and the other half is "away missions" to planets, other ships and space stations. There are a few videos on youtube of the demo that they presented at PAX earlier. It'll have all the most popular ships from the tv shows, fleets (guilds) and common areas to hang out such as Deep Space Nine, Quark's bar and all.
www.startrekonline.com