When I look to the future I first ask 'who was right about the place we've got to already?' And based on that I see the future as a merging of Phillip K. Dick and William Gibson where people exist in a state of corporate serfdom, with ever more people fighting for ever scarcer resources except for a small percentage at the top who will be afforded every luxury. So for the corporate managerial class the finest naturally produced hormones and no doubt by then grown and harvested organs for transplant. For the rest of us, back alley, slap-dash '->-bleeped-<- jobs' with hormones of doubtful origin.
And hey, I'm the optimist, most of my friends are much more pessimistic than I am.
I am quite sure that Mr. Dick had the concept of 'kibble' down pat and that's going to be a huge part of our world. Dick's saw a world that at the bottom, street-level, ground-level was basically a huge trashheap. It wasn't a problem of a few places, it was basically the entire ground area, the first few floors of every building. Though Dick never said why that was to happen, I think I figured it out (saw what he saw) and I'm watching it come true.
The whole biology thing might matter a whole lot less as more or less everything becomes more a replica than an original in terms of most things - not just gender.