Yes... Sad to say that depression has severely affected my life since about the age of 8. It seems to come in waves; with this last bout really coming when I was 20. It is like a pain in my soul, that numbs everything. I know there are those out there that believe that depression, or any psychological disorder for that manner, is "all in the head". But after experiencing it again and again, it is deeply rooted; as most of my family has experienced depression too. Whenever I am depressed, I have an increased level of apathy for others, think life is not worth living, increased cynicism, can't find joy front situations, etc. In other words, it sucks. Luckily, right now I am doing fine and without depression in my life. It has affected me fairly severely, though I have not seriously tried to take my own life. Depression is the worst for me.