I must say, my past, doing full contact martial arts, I was very well built for a male. 6 pack, large Biceps, rock solid triceps, chest well built and to top it off, I had a very thick neck.
Being on hormones for little over 3 months now, I have seen a massive (About 50 - 75%) decrease in muscle mass, and a gain of fat. I no longer have a 6 pack, my biceps are barely existant, I have granny flap underarms and triceps, and my neck has decreased in thickness. Before hormones I believe I weighed about 89KG or so. Now I way 72KG and generally am dropping half a kilo a day, with the exception of maybe the odd day or 2 where I put on half a kilo.
I take Androcur / Siterone (Cyproterone Acetate) which is known to have the best effect in muscle deterioration.
I am very pleased with my results so far, however, currently I have small hips, and not much fat distribution to my hips or anything.
FYI: I have been trying to put on weight LOL. It's just not working.