Although I don't like them I find alot of there behaviors depraved. I find the case Of the short lived emperor Elagabalus interesting as they seem to be almost certainly transsexual based on there behavior. because they were an emperor there behavior was well documented and I think proves the case that this isn't a recent social phenomenon.
Elagabalus' sexual orientation and gender identity are the source of much controversy and debate. Elagabalus married and divorced five women apparently without consummating most of them his most stable relationship seems to have been with his chariot driver, a blond slave from Caria named Hierocles, whom he referred to as his husband. Cassius Dio reported Elagabalus would paint his eyes, epilate his facial hair and wear wigs.
Herodian commented that Elagabalus pampered his natural good looks by wearing too much make-up. He was described as having been "delighted to be called the mistress, the wife, the Queen of Hierocles" and was said to have offered vast sums of money to the physician who could equip him with female genitalia.
In our more recent history David Remier, For showing biological innateness of our condition As horrific as the experiments performed on them were.