the girl who pierced my ears made one a little too close to edge so when I got fed up of it I held icecubes against earlobe and then shoved a big darning needle through without any pain.  I was surprised at how tough skin is though.
using ice first should make it easy to do own injections if need be but I must admit I turn my head away when nurses draw blood with those thick needles used for that.

I know this is a little old but i thought i'd weigh in. I do my shot once a week and the day sometimes varies between friday/saturday just depending on my schedule. im not a doc or anything but a day or two late every once in a while wont mess you up

Thanks man I went ahead and decided on late so I'm getting my next shot on Saturday. Decided that I'm gonna talk to the doc about every week or every 10 days next time so I won't have to stress next time.