I know this is an old topic but there's some useful information that is worth putting here:
LGBT Center of Raleigh is doing some trans support efforts now. I've not personally dealt with them (I live in Durham so they're out of my way a bit) but friends are involved.
NC Harms Reduction Coalition runs at support group in Chapel Hill, generally on alternating Wednesdays (and the meetings alternate being open to SOs, allies, etc., or closed) I've been to this one a few times; it's a small but great group.
There's a Trans Talk Tuesday group on the 2nd and 4th Tuesday of each month at Open Eye Cafe in Carrboro. This is another that I've not attended but wish to.