I've felt like I was going crazy, like literally going to end up in the asylum or something.
For me it has taken time for my body to get used to the hormone changes, and it's been bumpy at times for me. One big thing I noticed once I went full time (and started HRT) was that I became hyper aware of my body. I mean, for the first time in my life I really wanted to be in my body. I became hyper careful about wearing my seat belt, and driving carefully for example. But I also noticed other things, like when my body would twitch for example it would freak me out like something might be wrong, or if I got a headache I might think I had a brain tumor or something. I'd lie awake in bed at night freaking out that I had gone through all this stress of dealing with being trans and accepting this path only to die from some disease. Multiple times this has gone into full on panic attacks, and I've even lost sleep over it (which I always make up eventually, but still).
What's weird is that most days I feel totally normal and just like an average girl. I'm so content and happy and people around me even comment about how much more content and happy I seem compared to my old self. I think that my body must be going through stages of fighting the HRT or something sometimes because there are some days I just feel really off. Much more susceptible to anxiety and self doubt and fear.
One day about a month ago after a couple rough nights with anxiety and doubt I awoke to just find myself in a funk. Around noon I finally relented and just gave up. I thought maybe I was just crashing from transition and something was wrong. So I got out some boy clothes and just told myself I'd be a boy for the day. I got completely dressed in boy clothes, thinking that at least I'd find a little relief for a few hours while I sorted stuff out.
It did nothing. I still felt just as messed up as before. Being a boy didn't help. I still felt the same. Which actually cheered me up.

Boy mode wasn't the cure for me.
Anyway, I've been much better lately. I still have moments of panic and anxiety. I think I'm still getting used to this new body, and certainly getting used to caring about it and wanting it to be healthy. I don't actually go crazy, I just feel like I am sometimes.