However, for an honest appraisal, I will have to say that on the whole, I have had an overwhelmingly positive experience being openly transsexual. As someone who doesn't pass well, I don't have much choice there so I am totally embracing it instead of being ashamed of it. I can't hide in my house and still afford the procedures and hormones I need, so I just put on my big girl pants and get out there.
My coworkers have been fantastic. I've spoken one-on-one at great length with all of the women in my primary area of responsibility, and all of them have been very supportive. The one that knew me from before (I went to school with her daughter even) describes me as "radiant" because I am so happy all the time. :-D
The security badge I was issued only opens the women's restrooms, and security and HR are supportive of my right to use them. I've made it clear that I still tend to use the gender neutral ones at my workplace because I have an interest in not creating more of a hassle for myself by causing an incident, regardless of the support. But that, more than anything else, made me feel truly welcome in the workplace, to know that they wanted to be up front with my right to use the one I was most comfortable with.
I did have a minor, minor hiccup now that I am training in a new department. It's a different group and none of them knew me from before. At last I had to break the ice a couple nights ago and say, "Look, now that there's no one in line, I want you to know that it's true, I am in transition from male to female, and I have no problem talking about it. So don't feel awkward asking questions." Pretty much as soon as I finished saying that, one of my coworkers launched into, "So what's it like being on hormones?" :-P Sometimes they're just waiting for you to say it's ok, haha.
One more major thing I've noticed: No one respects my femininity until I tell them I'm trans. However, once I explain even just the bare minimum stuff—yes, hormones give me PMS and I do get more emotional; yes, I told my parents when I was 6 years old; yes, I am mostly interested in men now; yes, I do want children some day—I have what I've started to call a "keys to the clubhouse" moment: the women listening all collectively decide, "Yep, she's one of us. Welcome to the club. Here's your key. Meetings are on Saturdays. It's Liz's birthday next week, so she'll be bringing treats for everyone. . ." and I'm brought right in. But until that moment, it's this awkward, intangible, keeping-at-arm's-length uncertainty about me where I'm usually treated like some trumped up crossdresser people have to show at least a minimum amount of politeness toward. I like that moment, naturally, but I don't like needing to wait for it to be accepted.