be careful please kate, spiro can cause your potasiam levels to become quite high, i went to my doctor feeling very fatuged they checked my blood and found my potasiam to be dangerously high. and at that point i stopped taking spiro for a time. also i was not aware that spiro can cause some very nasty heart problems which cant easily be cured if at all. it can cause you to devolep and arithmia in your heart which means your heart is in the wrong rithum. i now have to take digitalis for my heart and also a blood thiner to keep from having a stroke. so please be careful, i no longer take spiro i have since had and orchiectomy, best decision i ever made, no more nasty antiandrogens just estrofem, good luck transitioning terribeth