Quote from: Laura91 on June 19, 2012, 06:54:08 PM
Well, that's cool for you. Have you experienced any emotional side effects from taking it?
No, and I have been on high-does finasteride for over 20 years.
I did a quick review of pub med, and the best I can found is that finasteride causes depresionn on rodents; and while there are a couple of studies in humans, the studies were not conclusive at all. See belo, for example
BMC Clin Pharmacol. 2006 Oct 7;6:7.
Finasteride induced depression: a prospective study.
Rahimi-Ardabili B, Pourandarjani R, Habibollahi P, Mualeki A.
Source
Clinical Pharmacy Laboratory, Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
ba.rahimi@gmail.comAbstract
BACKGROUND:
Finasteride is a competitive inhibitor of 5 alpha-reductase enzyme, and is used for treatment of benign prostatic hyperplasia and androgenetic alopecia. Animal studies have shown that finasteride might induce behavioral changes. Additionally, some cases of finasteride-induced depression have been reported in humans. The purpose of this study was to examine whether depressive symptoms or anxiety might be induced by finasteride administration.
METHODS:
One hundred and twenty eight men with androgenetic alopecia, who were prescribed finasteride (1 mg/day) were enrolled in this study. Information on depressed mood and anxiety was obtained by Beck Depression Inventory (BDI), and Hospital Anxiety and Depression Scale (HADS). Participants completed BDI and HADS questionnaires before beginning the treatment and also two months after it.
RESULTS:
Mean age of the subjects was 25.8(+/- 4.4) years. At baseline, mean BDI and HADS depression scores were 12.11(+/- 7.50) and 4.04(+/- 2.51), respectively. Finasteride treatment increased both BDI (p < 0.001) and HADS depression scores significantly (p = 0.005). HADS anxiety scores were increased, but the difference was not significant (p = 0.061).
CONCLUSION:
This preliminary study
suggests that finasteride
might induce depressive symptoms; therefore this medication should be prescribed cautiously for patients with high risk of depression. It seems that further studies would be necessary to determine behavioral effects of this medication in higher doses and in more susceptible patients