I agree with Jeanette. Recommendations will depend on your doctor and surgeon. Some allow for continuation of a small dose of Estrace, others not. Some ask that Spiro be stopped a couple of days before the surgery, some earlier.
My personal stance is that if we take non-oral bio-identical estradiol, then we are getting estrogen much the same way as ciswomen are so that if ciswomen are allowed to go through with major surgery without being asked to remove their ovaries or stop their body's production of estrogen, then why should we? The concern is formation of clots. Studies have shown that non-oral bio-identical estradiol has a negligible effect on coagulation, at high and low doses, in young and older individuals, men and women. I take estradiol by injections, my levels range from 1,000-4,000 pg/ml. Clotting times remained normal, on the three occasions when they were analyzed. If no one ever brings this up with their surgeons and/or doctors, nothing will ever change. Until then though, we are obligated to follow directives. We need to arrive at a consensus with them. Doing things behind a doctor's back is wrong and strongly discouraged in this forum.
Spironolactone interferes with electrolytes and this is why, I think, it needs to be stopped.
My 2 cents.
