Yes, it depends a lot on genetics. Some will have great success on a constant low dose, others not so much.
I've been doing the constant dose for six years, and I'm not happy yet. I have recently started cycling between E and P to see if anything changes. If not, I'll give up and go surgical.
I had such high hopes because people told me I could expect to be a cup size smaller than my closest female relatives. I thought, "Jackpot!" Both of my grandmothers, all of my aunts, and all of my cousins were huge but also overweight. Sadly, I inherited my great-grandfather's tall-and-skinny genes, and I passed that on to my daughter. < sigh >