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Anti-depressants?

Started by tammy753, May 31, 2026, 06:42:13 AM

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tammy753

May 31, 2026, 06:42:13 AM
My therapist has wanted to put me on anti-depressants for a while. I am thinking I need them to quite the negative thoughts in my head. Has anyone been prescribed them while on HRT. Anything I should watch out for. I fear living in a fog.
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Charlotte Kitty ✅

#1
May 31, 2026, 06:53:34 AM
I have been on antidepressants since 2010 with no break but have changed types. For me there is no fog or any identifiable symptoms from using them. If I forget a day then I know about it however! That said other people have different experiences and do get side effects, so it really depends on the person.

In terms of HRT there was no interaction at all. I'm on Venlafaxine which is a second line SNRI antidepressant. You'd probably start on a SSRI like Sertraline or Fluoxetine as they are far less stressful on your system and have very few interactions.

There is no problem being on them if you feel you need that help. And as long as you need too.

Charlotte 😻

ChrissyRyan

#2
May 31, 2026, 07:13:10 AM
No, I have not been prescribed any antidepressants.  I would think a MD would know of any side effects or adverse effects of you taking them with your HRT.  Each of us do react differently to meds but maybe the replies here would shed some light also.


Chrissy
Always stay cheerful, be polite, kind, and understanding. Accepting yourself as the woman you are is very liberating.  Never underestimate the appreciation and respect of authenticity.  Help connect a person to someone that may be able to help that person.  Be brave, be strong.  A TRUE friend is a treasure.  Relationships are very important, people are important, and the sooner we all realize that the better off the world will be.  Try a little kindness.  Be generous with your time, energy, wisdom, and resources.   Inconvenience yourself to help someone.   I am a brown eyed, brown haired woman. 

CosmicJoke

#3
May 31, 2026, 09:44:53 AM
Quote from: tammy753 on May 31, 2026, 06:42:13 AMMy therapist has wanted to put me on anti-depressants for a while. I am thinking I need them to quite the negative thoughts in my head. Has anyone been prescribed them while on HRT. Anything I should watch out for. I fear living in a fog.

I take an antidepressant and it really doesn't interact with my HRT at all. I recall going off the antidepressant once and it only really resulted in high anxiety and feeling on edge. (Nothing good.)

If you need to be on an antidepressant it's best to remain on it in my opinion.

tammy753

#4
May 31, 2026, 09:46:44 AM
My Agoraphobia means I haven't been to a doctor in over 10 years. So this will be through telehealth. They will probably make me go get blood test first. None of this is making me excited but my depression has been really bad the last few weeks to the point I have finally realized I need them.
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big kim

#5
May 31, 2026, 02:45:57 PM
I was on Sertraline for 2 years from 2011 til late 2013. No side effects.
 

PhilippaRees

#6
June 04, 2026, 06:08:14 AM
I'm not on HRT but I have been on anti depressants for just over a year. Even though I knew they would be OK I still took some persuading that I needed them. It turned out I absolutely did need them, they helped me through some of the lowest points of my life.
My view of them is that they are not the solution for depression they are there to stabilize your mood to give you the chance to fix the actual cause of it and you only need them for as long as it takes.
In my case I had improved enough to consider coming off them until something happened to tip me back down the rabbit hole somewhat. However out of that incident I discovered that I am probably trans and my mood improved massively.
I am optimistic that I will stop taking them in about 6 months when they have done their job. I do know people who have been on them for 10 years because they still need them but are completely fine with that. Its what is right for you.

In terms of side drug effects I have no fog with mine, in fact the fog I did have has cleared up so clearly this one is right for me. I did however have one of the major side effects listed.
I started on half dose but at my lowest that got increased to the max dose. After that I found myself being very very agitated to the point of pacing up and down a lot.
Once I went back to half dose everything returned to normal so half dose is about right for me. What got me through this I think is the combination of half dose and a good counselor.
I suspect that HRT won't interact very much but only a doctor can tell you for sure.

I hope this helps anyone considering anti-depressants.they are nothing to be afraid of and can be enormously helpful with good guidance.

Claire Rose

#7
Today at 12:19:18 PM
I'm not on HRT, but I recently started seeing a therapist and a psychiatrist.  I've never taken anti-depressants before, but recently on prozac.  It's been life-changing in a good way. So much more brain space, and it has been years since I have been this happy.  Really didn't know I was as depressed as I was, and how much time I was obsessing on gender was tied to it. (Still do but not have a bit more brain space and can think so much clearer) - Anyway, I figured I would share - hope that helps!  Best of luck to you!
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