Feelings and emotions are transmitted through the brain by traveling down a neuron in pulse fashion, stimulating little follicles on the end to release neurotransmitters which fill the gap to the next neuron and so on. Sometimes the neurotransmitters are dissolved or sucked back up too fast to be effective. The result is some funky feelings. In most people it's only temporary, and can be fixed with exercise,
music, sun, a hug (try to be drained on 12 hugs a day) or drugs. Also it's an all or none principle, either there is enough stimuli to create a pulse or their isn't. What you are feeling is what you are feeling, there's no such thing as a subdued emotion from a physical standpoint.
There is evidence surfacing that issues with serotonin, a primary neurotransmitter, are predated sometimes by years by issues with another substance which isn't even properly named yet. Symptoms include feeling drained, feelings of deja vu, or sudden alarm and a sense of impending doom even though everything is alright.
That being said the cause of your dismay is probably a result of something like that, especially being on hrt, and not demons or spirits. That's not to say witchcraft doesn't have a place, some of you people are remarkable light workers and notice the first few treatments involve reinvigorating the body and it's energy field, especially the 12 hugs a day
