This is all theory, so I am not looking for a lecture on how certain levels are dangerous etc etc.
The theory I have, is that in younger, healthy transsexuals, the body may not be as sensitive to the dangers of high estradiol levels as we have come to understand. In fact, I'd go so far as to say we have a propensity to physiologically accept high estradiol in a biological attempt to go through a second puberty.
Case study (on myself, 29 year old):
My first labs were taken as I was on my second month of HRT. Taking supposed high dosages of both estradiol, finasteride, and spiro. The results:
Testosterone: 25 ng/ml
Estradiol: 175 pg/ml
Dry skin, hair, low sex drive, slight progress in appearance, small nodules of breasts, sensitive nipples.
My second labs came back on the 5th month mark. Same dosages. Results:
Testosterone: 9 ng/ml
Estradiol: 722 pg/ml (This is "extremely high" according to practitioners)
Very healthy. Same symptoms, very rapid progress in appearance, A cup breasts, slightly less sensitive nipples.
Since then, my dosages were lowered. I rapidly dropped in Estradiol levels (down to 640 pg/ml) in less than 1 week. I was switched from pills to a form of injectable. My dosage roughly equaled (in volume) the amount I was taking in pill form, however I am now taking it weekly. This started 3 weeks ago.
No lab results yet, however the day after injecting, I am on an estrogen high. 3 days later, my skin and hair are rapidly becoming more oily, my nipples are almost insensitive, skin tone begins to masculinize, sex drive begins returning to normal, emotional state shifts slightly.
My theory is this as follows: my body has become accustomed to having, and utilizing extremely high levels of estradiol. Now, since I am taking weekly injections in what my doctor says is a high dosage (even though they are very comparable to what I was taking daily on pills), it is as if the estradiol in the injectable form is being released too rapidly, leaving very little estradiol going through the week to feed the new estradiol receptors. It is as if my endocrine system has literally began to believe it is going through a female puberty, and taking every drop of estrogen in my body, since rapid feminization (and continued good health) had occured with "extreme" blood levels.
BTW my form of injectables were cypionate, instead of the more commonly used valerate.
Either way, feel free to discuss your opinions.
