Well then, he should talk to the hundreds of transsexual women that have benefited greatly from the addition of progesterone to their regimen. And answer to the numerous studies out there that show, without a doubt, that progesterone promotes growth of certain structures in the breast that are NOT stimulated by estrogen alone. In fact, a study by his colleagues in the Netherlands (I've personally read several studies by Gooren so know about him) found that...
Short-Term and Long-Term Histologic Effects of Castration and Estrogen Treatment on Breast Tissue of 14 Male-to-Female Transsexuals in Comparison With Two Chemically Castrated Men
Kanhai, Robert C.J. M.D.; Hage, J. Joris M.D., Ph.D.; van Diest, Paul J. M.D., Ph.D.; Bloemena, Elisabeth M.D., Ph.D.; Mulder, J. Wiebe M.D., Ph.D.
Author Information
From the Departments of Plastic and Reconstructive Surgery (R.C.J.K., J.J.H., J.W.M.) and Pathology (P.J.v.D., E.B.), Academisch Ziekenhuis Vrije Universiteit, Amsterdam, The Netherlands.
Address correspondence and reprint requests to Dr. J. Joris Hage, Department of Plastic and Reconstructive Surgery, Academisch Ziekenhuis Vrije Universiteit, PO Box 7057, NL-1007 MB Amsterdam, The Netherlands.
"Only in male-to-female transsexuals in whom progestative chemical castration is combined with feminizing estrogen therapy will full acinar and lobular formation occur with hormonally stimulated nuclei and pseudolactational changes. Hence, combined progestative antiandrogens and estrogens are necessary for genetically male breast tissue to mimic the natural histology of the female breast"
"Because the nonprogestative chemical castration in our male patients treated for prostatic cancer did not result in full acinar and lobular formation, although progestative chemical castration combined with estrogen intake in the transsexual patients did, we conclude that exposure to exogenous estrogens and progestative drugs is needed to induce the occurrence of acini and lobules in chemically castrated men."
"such formation seems to decrease when progestative antiandrogen treatment is stopped after surgical castration."
So, his colleagues seem to suggest, based on their scientific observations that the addition of a progestin is necessary for full breast growth and DOES make a difference.
