Of course those previous facts cover a lot already - here is my personal experience
I have used pills, patches, subdermal and injected. of all of them I prefer injected now the pills did work fine for me as long as I was young but you have to remember to take them several times a day plus they are quite a bit more expensive and as you noted they are harder on the liver (since they pass through twice). subdermal works well as you just have it put in and forget but it has to be put in by a doctor (advantage here, no fear of needles, or at least only one for numbing of area for the insertion)
disadvantages of the patches I found was that they seemed to not work as well for me, the dosage seemed lower and they seemed to fall off a lot, which I worked out by cleaning the area better and then cleaning with alcohol then applying the patch. Then during removal there was residue which I removed with mineral oil.