Wow..that's extreme results in a short time. I've been on HRT for 6 months, and was in the beginning prescribed Estrodiol oral pills, and Spironolactone. Though now on Estrodiol Velerate, which is vial form for injections. But after my first week, I had tingling sensations through my body, and a sense of calm. If your depression is related from longing to be female, just wait a few weeks to a month, and your going to be feeling wonderful. I use to be depressed, sad even for the longest time, and after being on Estrodiol oral pills, it has went away 99%. I leave out the 1% for the fact that we are woman and were going to feel emotional at times, it's a given. It took about 3-4 weeks really to start noticing nipple tingling and sensitivity. Just wait until you get 2 months in and they start growing. XD lol they are going to sting a little, be very careful to not tap them against things. The pain is similar to being kicked in the lower region. Though I should say right quick, that being small framed has a big advantage in showing more feminine in the face sooner. But be careful because you need body fat to develop breast fat. I have a friend who has been on HRT for around 1 year and has no breasts what so ever, nor that feminine of a face. The estrogen in you body is trying to redistribute the fat and reshape muscles on the body and face and without that you won't see hardly any results. I'm currently at 160 lb. I don't look it but can see it in my belly. But the extra pudge I believe is helping to feed the "enhancements" that my body is trying to go through. So, just be cautious about how skinny you get. Being on estrogen is going to make gaining weight easier and losing it alot harder. Make sure you manage and watch what your eating while you transition, that way you can get the best results and quicker. =)