Pre-transition, I had a hard time with them. I always felt like an outsider in groups of guys, and they constantly did and said things that made me roll my eyes, and often made me downright mad that I had to be stuck being seen by society as a member of the same sex as them.
Pretty much every time I was in a group where machismo was going on, guys being guys, dirty jokes, stupid s***, too much drinking, bragging, showing off, swaggering, I just wanted to leave. I shrunk into the corner, as far away from them as possible, and just couldn't stand being around that behavior. Even though technically socially I was male at the time, I definitely always felt like the girl of the group every time I was around a group of guys, and just tended to shrink away from them and wonder what the hell could possibly be going through their heads to make them act like that.
So yeah... when machismo was going on, it made me pretty uncomfortable. I actually had to leave a room sometimes, go outside and cry for a while, maybe even just scream into the sky, just to get out the frustration of dysphoria that resulted from knowing that THESE were the people that everyone expected me to be like.
Not being forced to be male against my will, though, has significantly helped me get over my misandrist tendencies and view men and masculinity as different, yes, but still valuable. The big difference is that now when men act with machismo, it's not an insult to me anymore, it's actually a compliment, because it highlights my femaleness by contrast. Plus estrogen decided to make me attracted to guys, so I can't find it in myself to be uncomfortable around them anymore, I find a vast majority of the things they do to be downright charming and sweet. Getting over dysphoria heals a lot of hurt. I remember someone saying "I don't mind living in a man's world as long as I can be a woman in it." I guess I'm starting to feel the same. Guys can be guys, and I'm okay with that, as long as I don't have to be one of them.
And where being treated like a guy by a group of guys ALWAYS made me feel uncomfortable, there's almost never a time where guys are treating me like a girl where I feel uncomfortable. (Aside from the ones who decide to hit on me and are very insistent about it to the point where even after saying no, I have other plans, they still keep pushing. That's the only time I'm uncomfortable around guys nowadays.)
I still don't really relate to them, and they still make me roll my eyes from time to time, but the actual discomfort and feeling of needing to get away has thankfully gone.
