Eat, smoke... it's still self-medicating.
"DIY biology" is a crappy idea for all sorts of reasons; one of which is that GMO organisms do tend to get loose in the environment, and that has unintended consequences. Ask bees and butterflies about this. (If you can find any to ask...
I definitely agree that there's too many possible consequences as opposed to how much this could help some people, but with that said, research into such developments I think are always worth exploring.