You can be like most females, consider the source and just ignore him.
As a gender fluid person who used to move from one gender perspective to another, I know my female side thought men no better than apes. Just knee-jerk reactions, living for food, beer, and sex.
My male side thought women were beyond irrational and silly, not really worth listening to, people I needed to protect and take care of since they were like children.
Those attitudes were hard-wired, and separate in my brain..male traits on the right hemisphere of my brain, female traits on the left. When I started taking derris scandens, a local Thai herb, my two gender modes blended so I can now see both perspectives, and I can tell you right now, it's easier to ignore your brother, or to insult him back, toss your head, laugh, consider him a poor stupid male, and just move on, than to argue. It's not worth it.
Besides, as a female, you can control males. Just tell them what to do, make them feel like a hero and they'll knock themselves out for you. Ask me how I know.
Also, your brother is right. My male side was taken aback by sexually aggressive, pursuing females and I'd run for my life. My male side had to make the first move and do the courting, although most females know how to subtly encourage males. Just laugh at his jokes and glance at him, smile, and he's yours.
But acting sexually aggressive frightens my male side away. I suppose this is hard-wired to prevent males from choosing male-like females for spouses, who are less likely to be willing to take care of him and raise his progeny. Also, men talk to each other about their sexual conquests, so if many males are talking about a particular girl being "easy" that girl won't seem special when it comes to serious romance.