Ehhh it's hard to determine. First thing you should know that, depending on age, of course, the first year or so of HRT will be fraught with mood swings and irritability. These effects can and most likely will exacerbate any mood disorders you presently have (or may alleviate them, if the disorders are a product of dysphoria and not separate conditions unto themselves). I speak, of course, from personal experience and my insight should not be considered a suitable substitute for actual medical advice from a licensed physician. Talk to your doctor (but be warned, even they might not be able to tell you... like with any medication, it's all just a game of "let's wait and see).