I started out on a lowdose of evorel (gradually increasing over a 2 year period) , then due to circumstance, went on to finasteride. About 6 months later I changed to Sandrena gel and Decapeptyl. Dr advised me to stay on the finasteride for a couple of weeks when i changed over (to avoid a spike). I didn't notice a spike. But when it came to my next jab 3 months later, on having my second jab, I had an irritable mood for about 4 days and generally off colour and moody. Not sure if it was a coincidence. The next jab , I didn't notice anything.