First of all, the risk, even swallowed, even over 40, is LOWWWWWWWWW
Only non bio identicals like ethinilestradiol or Premarin induce a significan liver load.
Also, the reason for bypassing the liver is not because it loads it,
using tylenol is a much bigger treat to the liver than that,
its because the
byproducts of processing estrogen produce clotting agents which may induce DVT.
Again, that's unlikely with bio-identicals, especially if the dose is low.
Estrace works very work sublingually. Often, they don't mention it on the packaging
because every new mode of administration requires FDA testing and since estrogen
is such a generic medication, there's little money in that, so no company will
be for retesting for sublingual administration.
Also, the reason they promote pills instead of sublingual is that there is a higher compliance
in taking medication through pill form than having to hold a pill 5-10 minutes under your
tongue. Compliance is important in medication taking and people want their meds not
to take part of their day to administer.
If you want the pill to disolve quicker, abrade the coating with the tongue and then
let it disolve.
