Icephoenix and Ms. OBrien, I can totally relate. However, I lived enough years presenting in drag as a man that I can tell you it isn't the trans thing. I actually have more friends and better friends than I did before, but in both cases, its me.
I am still slowly undoing a lifetime of conditioning that told me I was only wantable and wanted inasmuch as I was useful and had something to contribute. Oddly, I never applied that to other people - I didn't expect anything from them, or them being able to give me things or do useful stuff for me, for me to like them - but I expected that of them regarding me, and if I didn't feel I had something to make their life great, I didn't reach out, I didn't call, I didn't pop in, I didn't make the gesture.
I laughed when I read this only because Ms. OBrien is a dear friend of MINE and she very much created and built that friendship despite my habitual disbelief that anyone could ever want to have anything to do with me. We don't get together or talk nearly as often as we would like, at my end because I'm still in the tail end of 15 years of controlling relationships where my every word and minute is monitored and reported to the woman in charge. I only exaggerate slightly.
Friendship, especially the close kind of friendship that occurs between women of the best friends variety, is a two-way street, and you can kill it by not needing anything as much as by needing everything.
It is a hard, hard habit for me to break, to not suffer and pull myself together alone, but to reach out when I am sad and broken and distraught and not in the least bit in control of my situation. I have been there for Ms OBrien, and she has been there for me, and we are both learning that that is ok!
It is also a hard, hard habit for me to break, to not smother the other person with supercharged concern, care, patience, generosity, whatever it takes to be worth knowing. LOL.
People are actual human beings, and actually tend to love actual human beings, so all my exhausting supergirl efforts were actually self-defeating in the friendship arena. Most people have some warts and like a friend with about as many warts as they have.
If you are in my area, I'd love to be your friend. Most of the time, its as easy as that. Some people's lives are too overwhelmed and full up to add another friend, and that's not a rejection, but there are many more of us who are starved for real sisterhood and real friendship, and we need to figure out how to find each other and get past our scars that say nobody wants us.