I'm pretty large guy to start with, and then I have some pretty infuriating D-cups to contend with. I have a long binder, so it pulls in my hips a little too, but it does have a habit of pulling in just under my ribs and digging in, and I can't eat an even vaguely large meal with it on. It helps me pass, and it's great to look down at my clothes once it's on and see everything sitting right, but it gets pretty uncomfortable. I have to be pretty strict with how long I wear it, too, or it gets painful. And then there's the sweat.
I'm really looking forward to top surgery.

I'll be happy to join in on the moaning! I've been binding for 6 1/2 years now, with absolutely no end in sight. I use Underworks binders, and have since I began binding, but over the years, these have caused my shoulders to become so damaged that if I raise my arms over shoulder level for more than about a minute a day, my bursitis (also caused by binding) flares up and gives me excruciating pain. I haven't noticed breathing problems, nor have I had the displeasure of enduring lung infections, but I'm always worried about that. I only have Bs, but they won't lay flat without a pretty strong binder no matter what I do. Years of binding has broken down the breast tissue somewhat, but apparently mine are just quite resistant.