You mean having no filters to preconceive with?
Number one, it's not impossible, I have chemically been perilously close to that, and if the consciousness is powerful enough, I do not necessarily see a big downside.
But that kitchen is pretty hot, so stay out of it if you can't cook with they got in there.
Or could you perhaps be suggesting a kind of empty or blank slate thing, where there is no personality after a point, in that case I'd say it's very close to impossible, and only desirable if there is some point of return.
My view is that casting aside the Ego, see: theda bardol, can be a pretty fast track to Enlightenment, and tends to be desirable.
But maybe I'm crazy...