It doesn't "per-say" but it does.
Heres what happened with me, I came out early, at the time I was 100% into females even thou I had never been with one.
Day 1 on HRT, still 100% females, day 100 on HRT still 100% females, day 101 on HRT 99% females within the first 12 months I was 100% bi but the idea of being with a guy freaked me out, maybe its because the idea of anal sex still freaks me out.
After SRS, i've been with 2 females and countless men, I'm now 100% straight.
As for sex drive, what a lot of people do not understand here is theres a difference between horny & turned on, I can wake up, but very horny, go all day feeling like I could jump someones bones and go to bed at night and not do a thing about it, its a feeling of happiness, you feel glowing all day really, for females there is no grey area, its horny & turned on.
If I'm turned on, which is something needs to be done, I can go find a showerhead, a toy or spend some "alone time" if I haven't got anyone. Once you cross that line you need to handle it. It also takes a "trigger" to jump that line.
For guys, there is a grey area, they can walk around, they can go for so long before they need to do something.