My only problem with the downstairs stuff is when it decides to engage in unnecessarily gross and painful reproductive-related functions. Otherwise I get along pretty well with that part of myself.
I mostly worry about my chest in an on-again, off-again way. I dress to show off my chest sometimes when I need confidence, and it definitely feels like drag performance but I get plenty of compliments. Then I go home and look down and I'm like "meh why am I so lumpy" and stress out about it.
I feel like it's definitely personal in terms of what your relationship is with your body, what it does for you, and what pains it has caused you in the past.