I'm happy to say my mother and step father have been supportive since day one. My father on the other hand, he's said some pretty nasty things. This was one of the last conversation I had with my father about a year ago after I came out to him:
Father: I know you were born this way, but you've lived 40 years as a male, you can suck it up and be a man and go back into the closet where you belong for another 40 years.
Me: So let me get this straight, you want me to go back in the closet life a unhappy and unfulfilled life because you can't deal with having a transgender daughter.
Father: You will always be "my son" and I love you, but no good will come of this. You'll loose your family, your friends, your business (my wife and I own a computer software company that does consulting and customization) and you marriage.
(He already knew my wife was accepting and pansexual before he said that. He had a conversation with my wife just before this privately teller her to woman up and keep me straight, making my wife cry.)
Me: Well Dad, I have nothing else to say but your wrong. I know you think your doing what's best for me, but you just plain wrong.
Father: All you are doing is being "self-serving" and again no good will come from going down this path. I pray for you.
Me: I'm sorry you feel this way. I see that you've made up your mind now and I might as well talk to that wall over there. My wife and and I are going now (we were leaving anyway from visiting him and left the restaurant heading to my wife's parents for a visit) I have to do what is best for me, and not what is best for you. This is something my wife also agrees with. I hope that someday you will see how wrong you are about this and accept me for who I am and not what you want me to be.
Father: I will always love you.
Me: I will to.
And we hugged and left and my wife and I decided not to tell her parents on that trip and we did end up telling them in January and that at first were non-supportive, but have come around and have been very accepting.
Since that day, I've left him two voicemails, sent him two E-MAILs and a hand written letter with no response. My letters were strong, but very positive. My last one (on Father's Day) I told him how non of the things he predicted came true. My marriage is stronger than ever. I didn't loose a single friend. The only family I lost was him, his 3rd wife, and two of his 3 sisters (all southern baptist). His other sister and I are close on Facebook and her husband (who was best friends with my father in high school) had a conversation with my father telling him how wrong he is about this. My letter stated how we didn't loose a single customer and things have been going well since going full time in March.
Since then, he started a FB account and added my brother, but blocked me and my wife. He didn't even bother to call or anything for my birthday in July. Maybe one day he will come around, but the way I see it, it's all on him now and it's his lose at this point.