I think it depends on what you take, like I've herd that some progestins n progesterone causes weight gain, but I know that Spironolactone will causes weight loss, I was using it at a mid dose n had to drop it right down to a low does, because I got far to thin n it messed with some other hormone called aldosterone n that messed with my nose n made me sniff alot because Spironolactone will block aldosterone in the adrenal glads but not some place in the nose, or something like that, it's one Med that really needs to, be monitored closely, so be shore to get your self a doctor, NO one else can give the proper treatment or advice.